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4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride, MP Biomedicals™

Catalog No. ICN19350391
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ICN19350391 1 g
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Catalog No. ICN19350391 Supplier MP Biomedicals Inc Supplier No. 0219350391
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Description

Offers many advantages compared to PMSF and DFP. 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride, MP Biomedicals is a covalent binding serine protease inhibitor. AEBSF belongs to the family of irreversible sulfonyl fluoride inhibitors that block tr

AEBSF is an irreversible serine protease inhibitor that has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. It is well suited for use in tissue culture media as well as in large scale purification of recombinant proteins, susceptible to proteolysis.

AEBSF is an alternative to PMSF, DFP and related organophosphate inhibitors.

  • Similar in structure, with similar inhibition constants
  • Lower molecular weight and toxicity
  • Offers better solubility in water, lower toxicity, greater stability and higher inhibitory activity

Chemical Identifiers

CAS 30827-99-7
Molecular Formula C8H11ClFNO2S
Molecular Weight (g/mol) 239.689
InChI Key WRDABNWSWOHGMS-UHFFFAOYSA-N
Synonym 4-2-aminoethyl benzenesulfonyl fluoride hydrochloride, aebsf, aebsf hydrochloride, pefabloc sc, aebsf hcl, pefabloc, 4-2-aminoethyl benzene-1-sulfonyl fluoride hydrochloride, aebsf, hydrochloride, benzenesulfonyl fluoride, 4-2-aminoethyl-, hydrochloride, 4-2-aminoethyl benzenesulfonylfluoride hydrochloride
PubChem CID 186136
IUPAC Name 4-(2-aminoethyl)benzenesulfonyl fluoride;hydrochloride
SMILES C1=CC(=CC=C1CCN)S(=O)(=O)F.Cl

Specifications

Melting Point 175°C to 185°C
Quantity 1 g
Solubility Information Soluble in methanol (10mg/mL, clear, colorless solution).
Formula Weight 239.7
Percent Purity ≥97%
Concentration or Composition (by Analyte or Components) Working Concentration: AEBSF has been used in cell culture in concentrations of up to 0.25mM.
Physical Form Powder

Safety and Handling

Recommended Storage Store at Room Temperature (15-30°C), desiccate, protect from light.