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3,4-Dichloroisocoumarin, 98%

Catalog No. AAJ65198MA
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AAJ65198MA 10 mg
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Catalog No. AAJ65198MA Supplier Thermo Scientific Chemicals Supplier No. J65198MA
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Description

CAS: 51050-59-0 | C9H4Cl2O2 | 215.03 g/mol

Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It is an inhibitor of Chymotrypsin and Trypsin. ,4 Dichloroisocoumarin also inhibits granzymes A, B, and H, cathepsin G, neutrophil elastase, proteinase and blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It is an inhibitor of Chymot

Chemical Identifiers

CAS 51050-59-0
Molecular Formula C9H4Cl2O2
Molecular Weight (g/mol) 215.03
MDL Number MFCD00036960
InChI Key SUGXUUGGLDCZKB-UHFFFAOYSA-N
Synonym 3,4-dichloroisocoumarin, 3,4-dcl, 1h-2-benzopyran-1-one,3,4-dichloro, 3,4-dci, 3,4 dichloroisocoumarin, 3,4-dichloro-1h-isochromen-1-one, 3,4-dichloro-1h-2-benzopyran-1-one, 1h-2-benzopyran-1-one, 3,4-dichloro, chembl24983, 3,4-dichloro-2-benzopyran-1-one
PubChem CID 1609
IUPAC Name 3,4-dichloroisochromen-1-one
SMILES ClC1=C(Cl)C2=CC=CC=C2C(=O)O1

Specifications

Color White
Quantity 10 mg
UN Number UN2811
Beilstein 6802625
Solubility Information Soluble in DMF or DMSO at a concentration of 10mM
Formula Weight 215.03
Percent Purity 99%
Physical Form Powder
Chemical Name or Material 3,4-Dichloroisocoumarin

Safety and Handling

Hazard Category H301-H315-H319-H335
Hazard Statement GHS H Statement
H301-H315-H319-H335
Toxic if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
TSCA No
Recommended Storage Keep cold

RUO – Research Use Only