Learn More
(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide, 98%
CAS: 52509-14-5 | C22H22BrO2P | 429.29 g/mol
Supplier: Thermo Scientific Chemicals A1888230
Description
It finds its applications as a reagent for Wittig olefinations with introduction of a 1,3-dioxolane moiety. It is applied as a reactant for the preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione, for microwave-assisted synthesis of KN-93 as inhibitor of calmodulin kinase II, for the preparation of fluorinated spirobenzofuran piperidines as s1 receptor ligands, in the synthesis and antitumor agents, in regio-selective preparation of indole derivatives via rhodium-catalyzed domino hydroformylation/indolization.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsIt finds its applications as a reagent for Wittig olefinations with introduction of a 1,3-dioxolane moiety. It is applied as a reactant for the preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione, for microwave-assisted synthesis of KN-93 as inhibitor of calmodulin kinase II, for the preparation of fluorinated spirobenzofuran piperidines as s1 receptor ligands, in the synthesis and antitumor agents, in regio-selective preparation of indole derivatives via rhodium-catalyzed domino hydroformylation/indolization.
Solubility
Soluble in water (20°C).
Notes
Hygroscopic. Store away from water/moisture and oxidizing agents. Store under inert gas. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
- Environmental benefits include:
- Source Reduction
Specifications
(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide | |
186°C to 189°C | |
MFCD00011966 | |
Hygroscopic | |
Soluble in water (20°C). | |
[Br-].C(C1OCCO1)[P+](C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1 | |
429.29 | |
429.3 |
52509-14-5 | |
C22H22BrO2P | |
250 g | |
1,3-dioxolan-2-ylmethyl triphenylphosphonium bromide, 1,3-dioxolan-2-yl methyl triphenylphosphonium bromide, 1,3-dioxolan-2-ylmethyl triphenylphosphanium bromide, phosphonium, 1,3-dioxolan-2-ylmethyl triphenyl-, bromide, 1,3-dioxolan-2-yl methyltriphenylphosphonium bromide, 1,3-dioxolan-2-ylmethyl triphenyl phosphanium bromide, 1,3-dioxolan-2-ylmethyl triphenyl phosphonium bromide, 1,3-dioxolan-2-ylmethyl triphenylphosphine, bromide, acmc-209kzy | |
FRHRVQQUICVJDG-UHFFFAOYSA-M | |
1,3-dioxolan-2-ylmethyl(triphenyl)phosphanium;bromide | |
2724194 | |
98% |
Chemical Identifiers
52509-14-5 | |
429.29 | |
FRHRVQQUICVJDG-UHFFFAOYSA-M | |
2724194 | |
[Br-].C(C1OCCO1)[P+](C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1 |
C22H22BrO2P | |
MFCD00011966 | |
1,3-dioxolan-2-ylmethyl triphenylphosphonium bromide, 1,3-dioxolan-2-yl methyl triphenylphosphonium bromide, 1,3-dioxolan-2-ylmethyl triphenylphosphanium bromide, phosphonium, 1,3-dioxolan-2-ylmethyl triphenyl-, bromide, 1,3-dioxolan-2-yl methyltriphenylphosphonium bromide, 1,3-dioxolan-2-ylmethyl triphenyl phosphanium bromide, 1,3-dioxolan-2-ylmethyl triphenyl phosphonium bromide, 1,3-dioxolan-2-ylmethyl triphenylphosphine, bromide, acmc-209kzyShow More | |
1,3-dioxolan-2-ylmethyl(triphenyl)phosphanium;bromide |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302+H312+H332-H315-H319-H335
EINECSNumber : 257-977-3
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only