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Tocris Bioscience™ WAY 252623

Catalog No. 595110
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595110 10 mg
595150 50 mg
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Catalog No. 595110 Supplier Tocris Bioscience™ Supplier No. 5951/10

Description

Potent LXR agonist

WAY 252623 is a potent LXR agonist (IC50 values are 24 and 179 nM for LXRβ and LXRα, respectively). Reduces total serum cholesterol and LDL cholesterol, and inhibits lesion growth in models of atherosclerosis. Increases ABCA1 and ABCG1 mRNA levels in rat peripheral blood cells. Orally bioavailable.

Specifications

Chemical Name or Material 2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
CAS 875787-07-8
Quantity 10 mg
Target LXR-like Receptor Agonists
Molecular Formula C21H12ClF5N2
Formula Weight 422.78
Purity >98%