Cytiva Vivaspin™ 500 Sample Concentrators

Up to 30-fold concentration of the sample can be achieved with recovery of the target molecule typically exceeding 95%. Patented dead-stop technology ensures that samples cannot be concentrated to dryness and enables direct concentrate recovery.

• Accept sample volumes from 100μLto 20mL, with a range of molecular weight cutoff values from M_r3000 to 100,000
• Vertical polyethersulfone semi-permeable membrane separating upper and lower chamber resists blockage and tolerates high flow rate
• Centrifugation forces solvent through membrane, leaving concentrated sample in the upper chamber
• Compatible pH range: 1 to 9
• Active membrane area: 0.5cm²

For maximum recovery, select a MWCO at least 50% smaller than the molecular size of the species of interest.