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Tocris Bioscience™ VH 032, amine

Catalog No. 6462100
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100 mg
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6462100 100 mg
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Catalog No. 6462100 Supplier Tocris Bioscience™ Supplier No. 6462/100
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Description

Functionalized VHL ligand for PROTACs

VH 032, amine is a derivative of the von Hippel-Lindau (VHL) ligand, VH 032; commonly used as a precursor to a PROTAC® that hijacks VHL as the E3 ubiquitin ligase component. Supplied with a primary amine functional handle at a position known not to significantly affect binding to VHL, for ready conjugation to a linker/target protein ligand.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Require a different derivative? Get in touch

Specifications

Chemical Name or Material (4 R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide dihydrochloride
CAS 2137142-47-1
Synonym (4R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide hydrochloride
Quantity 100 mg
Target Degrader Building Blocks
Molecular Formula C22H30N4O3S0.2 HCl
Formula Weight 467.02
Purity 98%