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Thermo Scientific Chemicals U0126, ≥99%

Selective inhibitor of mitogen-activated protein kinases MEK-1 and MEK-2

$346.90 - $617.71

Chemical Identifiers

CAS 109511-58-2
Molecular Formula C18H16N6S2
Synonym 1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ61246MC
View Documents Promotion Details
Thermo Scientific Chemicals
J61246MC
100 mg
Each for $617.71
 
AAJ61246MB
View Documents Promotion Details
Thermo Scientific Chemicals
J61246MB
25 mg
Each for $346.90
 
Description

Description

U0126, is used as a selective MAP Kinase Kinase (MKK, MEK) inhibitor. U-0126 has been observed to inhibit promoters containing an AP-1 response element, while in contrast having no effect on promoters that lack an AP-1 response group. U-0126 is also useful in neuronal studies in mice since it displays inhibitory effects against oxidative stress. U-0126 is an activator of PGC-1, mtTFA and nuclear respiratory factor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

109511-58-2
C18H16N6S2
1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene

Specifications

100 mg
-30°C to -10°C
Selective inhibitor of mitogen-activated protein kinases MEK-1 and MEK-2
C18H16N6S2
1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene
Signal Transduction Reagent
≥99%
White
Powder
109511-58-2
380.49g/mol
Soluble in DMSO; Poorly soluble in ethanol and water
Powder
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS

RUO – Research Use Only