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TSKgel™ SuperSW mAb HR HPLC Column, 4 μm Particle Size, Sold by MilliporeSigma™ Supelco™
TSKgel™ superSW mAb HR HPLC column may be used in the separation of monoclonal antibodies using size exclusion chromatography (SEC).
Supplier: Merck Emd Millipore 822855
Description
TSKgel™ SuperSW HR mAb columns are designed for the separation and analysis of monoclonal antibodies (mAb). While mAbs can be analyzed using many different modes of HPLC, size exclusion is best to determine the level of aggregation, dimer formation, and fragmentation, making it the best method for heterogeneity studies. TSKgel™ SuperSW mAb HR columns are optimized for high resolution analysis of mAb monomer and dimer; these 30 cm x 7.8 mm I.D. slica-based stainless steel columns offer reduced lot-to-lot variation, long column life, reduction of unspecified adsorption, and superior recovery of aggregates. The calibration curve for the TSKgel™ SuperSW mAb HR column is similar to that of the industry-leading TSKgel™ G3000SWxl column and has a shallower slope than the TSKgel™ UltraSW Aggregate column around the molecular weight range of gamma-globulin. This shallow calibration curve produces high resolution separations.Order Info
Shipped in 0.05% NaN3 and 0.1 M Na2SO4 in 0.1 M phosphate buffer, pH 6.7.
Specifications
| 4.6 mm | |
| 15 cm | |
| 4 μm | |
| 250 Å | |
| 10°C to 30°C | |
| Diol | |
| Silica Particle Platform | |
| Stainless Steel |
| 0.5 mL/min. | |
| 80 bar | |
| 2.5 - 7.5 | |
| 0 to 100% aqueous soluble organic solvents | |
| L20, L59 | |
| TSKgel | |
| Size Exclusion |
TSKgel is a registered trademark of Tosoh Corporation