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TSKgel™ SuperSW mAb HR HPLC Column, 4 μm Particle Size, Sold by MilliporeSigma™ Supelco™

Catalog No. 111022195
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Length (Metric):
15 cm
30 m
Diameter (Metric):
4.6 mm
7.5 mm
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Catalog No. Length (Metric) Diameter (Metric)
111022195 15 cm 4.6 mm
111022194 30 m 7.5 mm
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Catalog No. 111022195 Supplier Merck Emd Millipore Supplier No. 822855

TSKgel™ superSW mAb HR HPLC column may be used in the separation of monoclonal antibodies using size exclusion chromatography (SEC).

TSKgel™ SuperSW HR mAb columns are designed for the separation and analysis of monoclonal antibodies (mAb). While mAbs can be analyzed using many different modes of HPLC, size exclusion is best to determine the level of aggregation, dimer formation, and fragmentation, making it the best method for heterogeneity studies. TSKgel™ SuperSW mAb HR columns are optimized for high resolution analysis of mAb monomer and dimer; these 30 cm x 7.8 mm I.D. slica-based stainless steel columns offer reduced lot-to-lot variation, long column life, reduction of unspecified adsorption, and superior recovery of aggregates. The calibration curve for the TSKgel™ SuperSW mAb HR column is similar to that of the industry-leading TSKgel™ G3000SWxl column and has a shallower slope than the TSKgel™ UltraSW Aggregate column around the molecular weight range of gamma-globulin. This shallow calibration curve produces high resolution separations.

Order Info

Shipped in 0.05% NaN3 and 0.1 M Na2SO4 in 0.1 M phosphate buffer, pH 6.7.

Specifications

Diameter (Metric) 4.6 mm
Flow Rate 0.5 mL/min.
Length (Metric) 15 cm
Max. Pressure 80 bar
Particle Size 4 μm
pH 2.5 - 7.5
Pore Size 250 Å
Solvents 0 to 100% aqueous soluble organic solvents
Temperature 10°C to 30°C
USP Type L20, L59
Stationary Phase Diol
Product Line TSKgel
Matrix Silica Particle Platform
Phase Size Exclusion
Material Stainless Steel
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TSKgel is a registered trademark of Tosoh Corporation