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Trifluoroacetic anhydride, 99+%
CAS: 407-25-0 | C4F6O3 | 210.03 g/mol
Supplier: Thermo Scientific Chemicals A1361414
Description
Trifluoroacetic anhydride is used for the introduction of trifluoroacetyl group in organic synthesis. It is involved in the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for gas chromatography analysis. It plays an important role as desiccant for trifluoroacetic acid. It is also used in the oxidation of aldehydes to acids, esters, amides as well as in the protection of alcohols and amines. In addition, it is used as analytical reagents, solvents and dehydration condensing agent. It serves as an intermediate of fluorine fine chemicals, pharmaceuticals and agrochemicals.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsTrifluoroacetic anhydride is used for the introduction of trifluoroacetyl group in organic synthesis. It is involved in the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for gas chromatography analysis. It plays an important role as desiccant for trifluoroacetic acid. It is also used in the oxidation of aldehydes to acids, esters, amides as well as in the protection of alcohols and amines. In addition, it is used as analytical reagents, solvents and dehydration condensing agent. It serves as an intermediate of fluorine fine chemicals, pharmaceuticals and agrochemicals.
Solubility
Miscible with benzene, dichloromethane, diethyl ether, dimethylformamide, terahydrofuran and acetonitrile.
Notes
Hygroscopic and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases, strong acids, and alcohols.
Specifications
| Trifluoroacetic anhydride | |
| -65°C | |
| 39°C to 40°C | |
| 1.269 | |
| MFCD00000416 | |
| UN3265 | |
| Moisture sensitive | |
| Miscible with benzene,dichloromethane,diethyl ether,dimethylformamide,terahydrofuran and acetonitrile. | |
| FC(F)(F)C(=O)OC(=O)C(F)(F)F | |
| 210.03 | |
| 210.03 |
| 407-25-0 | |
| 1.503 | |
| C4F6O3 | |
| (CF3CO)2O | |
| 25 g | |
| 746197 | |
| trifluoroacetic anhydride, trifluoroacetic acid anhydride, 2,2,2-trifluoroacetic anhydride, bis trifluoroacetic anhydride, acetic acid, trifluoro-, anhydride, perfluoroacetic anhydride, trifluoroacetyl anhydride, tfaa, hexafluoroacetic anhydride, anhydrid kyseliny trifluoroctove | |
| QAEDZJGFFMLHHQ-UHFFFAOYSA-N | |
| (2,2,2-trifluoroacetyl) 2,2,2-trifluoroacetate | |
| 9845 | |
| ≥99% |
Chemical Identifiers
| 407-25-0 | |
| 210.03 | |
| QAEDZJGFFMLHHQ-UHFFFAOYSA-N | |
| 9845 |
| C4F6O3 | |
| MFCD00000416 | |
| trifluoroacetic anhydride, trifluoroacetic acid anhydride, 2,2,2-trifluoroacetic anhydride, bis trifluoroacetic anhydride, acetic acid, trifluoro-, anhydride, perfluoroacetic anhydride, trifluoroacetyl anhydride, tfaa, hexafluoroacetic anhydride, anhydrid kyseliny trifluoroctove | |
| FC(F)(F)C(=O)OC(=O)C(F)(F)F |
Safety and Handling
GHS H Statement
H314-H318-H332
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if inhaled.
P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
H314-H332-H335
DOTInformation : Transport Hazard Class: 8; Packing Group: I; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber : 206-982-9
RTECSNumber : AJ9800000
TSCA : Yes
Recommended Storage : Keep cold; Store under Nitrogen
RUO – Research Use Only