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Trifluoroacetic anhydride, 99+%

CAS: 407-25-0 | C4F6O3 | 210.03 g/mol

$54.42 - $1529.79

Chemical Identifiers

CAS 407-25-0
Molecular Formula C4F6O3
Molecular Weight (g/mol) 210.03
MDL Number MFCD00000416
InChI Key QAEDZJGFFMLHHQ-UHFFFAOYSA-N
Synonym trifluoroacetic anhydride, trifluoroacetic acid anhydride, 2,2,2-trifluoroacetic anhydride, bis trifluoroacetic anhydride, acetic acid, trifluoro-, anhydride, perfluoroacetic anhydride, trifluoroacetyl anhydride, tfaa, hexafluoroacetic anhydride, anhydrid kyseliny trifluoroctove
PubChem CID 9845
SMILES FC(F)(F)C(=O)OC(=O)C(F)(F)F
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AAA1361414
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Thermo Scientific Chemicals
A1361414
25 g
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AAA1361422
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Thermo Scientific Chemicals
A1361422
100 g
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AAA1361436
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A1361436
500 g
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AAA136140E
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A136140E
2500 g
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Description

Description

Trifluoroacetic anhydride is used for the introduction of trifluoroacetyl group in organic synthesis. It is involved in the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for gas chromatography analysis. It plays an important role as desiccant for trifluoroacetic acid. It is also used in the oxidation of aldehydes to acids, esters, amides as well as in the protection of alcohols and amines. In addition, it is used as analytical reagents, solvents and dehydration condensing agent. It serves as an intermediate of fluorine fine chemicals, pharmaceuticals and agrochemicals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trifluoroacetic anhydride is used for the introduction of trifluoroacetyl group in organic synthesis. It is involved in the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for gas chromatography analysis. It plays an important role as desiccant for trifluoroacetic acid. It is also used in the oxidation of aldehydes to acids, esters, amides as well as in the protection of alcohols and amines. In addition, it is used as analytical reagents, solvents and dehydration condensing agent. It serves as an intermediate of fluorine fine chemicals, pharmaceuticals and agrochemicals.

Solubility
Miscible with benzene, dichloromethane, diethyl ether, dimethylformamide, terahydrofuran and acetonitrile.

Notes
Hygroscopic and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases, strong acids, and alcohols.
Specifications

Chemical Identifiers

407-25-0
210.03
QAEDZJGFFMLHHQ-UHFFFAOYSA-N
9845
C4F6O3
MFCD00000416
trifluoroacetic anhydride, trifluoroacetic acid anhydride, 2,2,2-trifluoroacetic anhydride, bis trifluoroacetic anhydride, acetic acid, trifluoro-, anhydride, perfluoroacetic anhydride, trifluoroacetyl anhydride, tfaa, hexafluoroacetic anhydride, anhydrid kyseliny trifluoroctove
FC(F)(F)C(=O)OC(=O)C(F)(F)F

Specifications

407-25-0
1.503
C4F6O3
(CF3CO)2O
25 g
746197
trifluoroacetic anhydride, trifluoroacetic acid anhydride, 2,2,2-trifluoroacetic anhydride, bis trifluoroacetic anhydride, acetic acid, trifluoro-, anhydride, perfluoroacetic anhydride, trifluoroacetyl anhydride, tfaa, hexafluoroacetic anhydride, anhydrid kyseliny trifluoroctove
QAEDZJGFFMLHHQ-UHFFFAOYSA-N
(2,2,2-trifluoroacetyl) 2,2,2-trifluoroacetate
9845
≥99%
-65°C
39°C to 40°C
1.269
MFCD00000416
UN3265
Moisture sensitive
Miscible with benzene,dichloromethane,diethyl ether,dimethylformamide,terahydrofuran and acetonitrile.
FC(F)(F)C(=O)OC(=O)C(F)(F)F
210.03
210.03
Trifluoroacetic anhydride
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Safety and Handling

Safety and Handling

GHS H Statement
H314-H318-H332
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if inhaled.

P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

H314-H332-H335

DOTInformation : Transport Hazard Class: 8; Packing Group: I; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.

EINECSNumber : 206-982-9

RTECSNumber : AJ9800000

TSCA : Yes

Recommended Storage : Keep cold; Store under Nitrogen

SDS
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RUO – Research Use Only