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Tocris Bioscience™ TPEN

Catalog No. 4309100
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100 mg
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Catalog No. Quantity
4309100 100 mg
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Catalog No. 4309100 Supplier Tocris Bioscience™ Supplier No. 4309/100
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Description

Cell-permeable Zn2+ chelator; also inhibits RNA binding protein Lin28

Heavy metal chelator. Reacts with both Zn-proteome and Zn-metallothionein (MT) in LLC-PK1 cells; acts as an intracellular chelator of proteomic Zn2+. Activity decreases intracellular zinc levels, and induces apoptosis in HeLa and cultured human retinal pigment epithelium (RPE) cells. Also inhibits RNA binding protein Lin28 (IC50 = 2.5 μM). Cell permeable.

Chemical Identifiers

CAS 16858-02-9
Molecular Formula C26H28N6

Specifications

Quantity 100 mg
Formula Weight 424.54
Purity >98%
Molecular Weight (g/mol) 424.55
Chemical Name or Material TPEN

Safety and Handling

Recommended Storage Store at +4°C