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Tolnaftate

Antifungal agent | CAS: 2398-96-1 | C19H17NOS | 307.411 g/mol

Supplier: Thermo Scientific Chemicals J6183406

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Catalog No. AAJ6183406

$336.45 / Each

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Description

Tolnaftate is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections such as athlete?s foot, jock itch, and ringworm1. It also has been used as a comparator compound for antifungal efficiency studies.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in chloroform at 50 mg/ml. Sparingly soluble in ethanol or methanol

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C

Specifications

Type	Tolnaftate
Physical Form	Powder
Melting Point	110°C to 113°C
Quantity	5 g
MDL Number	MFCD00056611
Synonym	Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester; Carbamothioic acid
InChI Key	FUSNMLFNXJSCDI-UHFFFAOYSA-N
IUPAC Name	O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate
PubChem CID	5510
Formula Weight	307.41

Chemical Name or Material	Tolnaftate
CAS	2398-96-1
Color	White
Molecular Formula	C19H17NOS
Merck Index	14,9519
Solubility Information	Soluble in chloroform at 50 mg/ml; Sparingly soluble in ethanol or methanol
SMILES	CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2
Molecular Weight (g/mol)	307.411
ChEBI	CHEBI:9620

Chemical Identifiers

CAS	2398-96-1
Molecular Weight (g/mol)	307.411
InChI Key	FUSNMLFNXJSCDI-UHFFFAOYSA-N
PubChem CID	5510
IUPAC Name	O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate

Molecular Formula	C19H17NOS
MDL Number	MFCD00056611
Synonym	Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester; Carbamothioic acidShow More Show Less
ChEBI	CHEBI:9620
SMILES	CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2

Product Suggestions Safety and Handling

Safety and Handling

EINECSNumber : 219-266-6

TSCA : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only

Tolnaftate

Description

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Chemical Identifiers

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