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Tolnaftate
Antifungal agent | CAS: 2398-96-1 | C19H17NOS | 307.411 g/mol
$111.26 - $1,211.71
Chemical Identifiers
| CAS | 2398-96-1 |
|---|---|
| Molecular Formula | C19H17NOS |
| Molecular Weight (g/mol) | 307.411 |
| MDL Number | MFCD00056611 |
| InChI Key | FUSNMLFNXJSCDI-UHFFFAOYSA-N |
| Synonym | Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester; Carbamothioic acid |
| PubChem CID | 5510 |
| ChEBI | CHEBI:9620 |
| IUPAC Name | O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate |
| SMILES | CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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AAJ6183403
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N/A | 1 g |
Each for $111.26
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AAJ6183406
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N/A | 5 g |
Each for $349.93
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AAJ6183414
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N/A | 25 g |
Each for $1,211.71
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Description
Tolnaftate is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections such as athlete?s foot, jock itch, and ringworm1. It also has been used as a comparator compound for antifungal efficiency studies.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilitySoluble in chloroform at 50 mg/ml. Sparingly soluble in ethanol or methanol
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C
Chemical Identifiers
| 2398-96-1 | |
| 307.411 | |
| FUSNMLFNXJSCDI-UHFFFAOYSA-N | |
| 5510 | |
| O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate |
| C19H17NOS | |
| MFCD00056611 | |
| Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester; Carbamothioic acid | |
| CHEBI:9620 | |
| CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2 |
Specifications
| Tolnaftate | |
| 2398-96-1 | |
| White | |
| MFCD00056611 | |
| Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester; Carbamothioic acid | |
| FUSNMLFNXJSCDI-UHFFFAOYSA-N | |
| O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate | |
| 5510 | |
| 307.41 |
| Powder | |
| 110°C to 113°C | |
| C19H17NOS | |
| 14,9519 | |
| Soluble in chloroform at 50 mg/ml; Sparingly soluble in ethanol or methanol | |
| CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2 | |
| 307.411 | |
| CHEBI:9620 | |
| Tolnaftate |
Safety and Handling
EINECSNumber : 219-266-6
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only