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Tocris Bioscience™ Terfenadine

Catalog No. 394850
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50 mg
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Catalog No. Quantity
394850 50 mg
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Catalog No. 394850 Supplier Tocris Bioscience™ Supplier No. 3948/50
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Description

H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker

Histamine H1 receptor antagonist. Also blocks KV11.1 (hERG) and Kir6 (KATP) channels (IC50 values are 204 nM and 1.2 μM respectively). Inhibits the delayed rectifier K+ current (IKr) in guinea pig ventricular myocytes (IC50 = 50 nM). Activity prolongs QT and induces Torsades de pointes (TdP); cardiotoxic in vivo.

Chemical Identifiers

CAS 50679-08-8
Molecular Formula C32H41NO2

Specifications

Quantity 50 mg
Formula Weight 471.67
Purity >98%
Molecular Weight (g/mol) 471.69
Chemical Name or Material Terfenadine

Safety and Handling

Recommended Storage Store at +4°C