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Tocris Bioscience™ TDZD 8

Catalog No. 609210
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609210 10 mg
609250 50 mg
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Catalog No. 609210 Supplier Tocris Bioscience™ Supplier No. 6092/10
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Selective non-ATP competitive inhibitor of GSK 3β

TDZD 8 is a selective non-ATP competitive inhibitor of GSK 3β (IC50 = 2 μM); thiadiazolidinone deriviative. Does not inhibit Cdk-1/cyclin B, CK-II, PKA or PKC at >100 μM. Reduces severity of L-dopa-induced dyskinesia in a Parkinson's disease in vivo model.

Specifications

CAS 327036-89-5
Quantity 10 mg
Solubility Soluble to 100mM in DMSO, 100mM in ethanol
Molecular Formula C10H10N2O2S
Formula Weight 222.26g/mol
Color White
Product Type Inhibitor

For Research Use Only