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  6. Thermo Scientific™ Sulfo-NHS (N-hydroxysulfosuccinimide), No-Weigh™ Format

Thermo Scientific™ Sulfo-NHS (N-hydroxysulfosuccinimide), No-Weigh™ Format

Catalog No. PIA39269
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10 x 2 mg
500 mg
5 g
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Catalog No. Quantity
PIA39269 10 x 2 mg
PI24510 500 mg
PI24525 5 g
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Catalog No. PIA39269 Supplier Thermo Scientific™ Supplier No. A39269
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Description

Prepare amine-reactive sulfo-NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysulfosuccinimide, CAS 106627-54-7.

Thermo Scientific™ Pierce Sulfo-NHS is pure N-hydroxysulfosuccinimide, the essential compound needed to prepare water-soluble, amine-reactive NHS-ester crosslinkers or to enhance conjugation efficiencies when using the carbodiimide EDC.

  • Chemical modification reagent for converting carboxyl groups to amine-reactive NHS esters for bioconjugation, crosslinking, labeling and immobilization methods
  • Efficiency of EDC-mediated coupling is increased in the presence of Sulfo-NHS
  • Amine-reactive NHS esters or Sulfo-NHS esters can be made with any carboxyl-containing molecule
  • Sulfo-NHS derivatives are usually directly water-soluble (can be added directly to physiologic buffers) and membrane-impermable (can be used for cell surface labeling)
  • High-purity, crystalline Sulfo-NHS can be used to create high-quality activated derivatives

Specifications

Chemical Reactivity Amine-Carboxyl
Cleavable No
Description Sulfo-NHS
Molecular Weight (g/mol) 217.13
PEGylated No
Spacer Arm Length Short
Content And Storage Upon receipt store at 4°C.
Cell Permeability No
Shipping Condition Ambient
Product Line No-Weigh
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Sulfo-NHS Ester
Spacer Short (<10 Å)
Form Solid
Quantity 10 x 2 mg
Solubility Water
Format Standard, Single-use, Premium-grade
Water Soluble Yes
Product Type Crosslinker
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Frequently Asked Questions (FAQs)

Can you provide the shelf-life for Sulfo-NHS (N-hydroxysulfosuccinimide)?

Sulfo-NHS (N-hydroxysulfosuccinimide) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended (4 degrees C). Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.
Can you provide the shelf life for Sulfo-NHS (N-hydroxysulfosuccinimide)?

Sulfo-NHS is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf).

How does a product with "No-Weigh" format reduce my concern over reagent stability?

The No-Weigh product format, where small amounts of reagent are pre-weighed and packaged separately, prevents the contamination and loss of reagent reactivity over time associated with repetitive opening and closing of a single vial. This format enables use of a fresh vial of reagent each time and eliminates the hassle of weighing out small amounts of reagent. Please view additional information and the video at: https://www.thermofisher.com/us/en/home/life-science/protein-biology/protein-labeling-crosslinking/no-weigh-packaging.html

For Research Use Only. Not for use in diagnostic procedures.