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Invitrogen™ STAT6 Polyclonal Antibody
Rabbit Polyclonal Antibody
$790.55
Specifications
| Antigen | STAT6 |
|---|---|
| Concentration | 0.28 mg/mL |
| Content And Storage | -20°C, Avoid Freeze/Thaw Cycles |
| Applications | ChIP Assay, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
PIPA532603
|
Invitrogen™
PA532603 |
500 μL |
Each for $790.55
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Description
This antibody is predicted to react with canine, mouse, porcine, rabbit based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is placenta or tonsil tissue.
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.Specifications
| STAT6 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human | |
| STAT6 | |
| 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT | |
| STAT6 | |
| Primary | |
| Antigen Affinity Chromatography |
| 0.28 mg/mL | |
| ChIP Assay, Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 1% BSA and 0.1% sodium azide; pH 7.6 | |
| P42226 | |
| 6778 | |
| Synthetic peptide derived from C-terminus of human STAT6. | |
| Antibody |