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Invitrogen™ Sortilin Recombinant Rabbit Monoclonal Antibody (23GB4170)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA553703

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Catalog No. MA553703


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Description

Description

Sortilin Recombinant Monoclonal Antibody for Western Blot

Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also, Sortilin acts as a receptor for neurotensin.
Specifications

Specifications

Sortilin
Recombinant Monoclonal
Unconjugated
Sort1
100 kDa NT receptor; 2900053A11Rik; AI852375; Glycoprotein 110; glycoprotein 95; Gp110; Gp95; LDLCQ6; mNTR3; neurotensin receptor 3; NT3; NTR3; Nts3; Ntsr3; Sort1; Sortilin; sortilin 1
Rabbit
Affinity Chromatography
RUO
6272
-20°C
Liquid
Western Blot
23GB4170
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q99523
Sort1
A synthesized peptide derived from Sortilin (650-770AA).
20 μL
Primary
Human
Antibody
IgG
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