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  8. (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%

Catalog No. p-7026852
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Quantity:
500 mg
2.5 g
Catalog No. Quantity
AAB23117ME 500 mg
AAB2311788 2.5 g
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Catalog No. AAB23117ME

Supplier: Thermo Scientific Chemicals B23117ME

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Description

CAS: 17257-71-5 | C10H8F3O3 | 233.17 g/mol

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is used as a chiral derivatizing agent, it reacts with an alcohol or amine of unknown stereochemistry to form an ester or amide. The absolute configuration of the ester or amide is then determined by proton and/or 19F NMR spectroscopy.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is used as a chiral derivatizing agent, it reacts with an alcohol or amine of unknown stereochemistry to form an ester or amide. The absolute configuration of the ester or amide is then determined by proton and/or 19F NMR spectroscopy.

Solubility
Readily soluble in hexane, ether, THF, CH2Cl2, benzene.

Notes
Hygroscopic. Store under inert gas. Store away from oxidizing agents, moisture.

Chemical Identifiers

CAS 17257-71-5
Molecular Formula C10H8F3O3
Molecular Weight (g/mol) 233.17
MDL Number MFCD00064200
InChI Key JJYKJUXBWFATTE-VIFPVBQESA-M
Synonym s---alpha-methoxy-alpha-trifluoromethyl phenylacetic acid, s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid, --mosher's acid, --mtpa, unii-172hcj1iqv, 172hcj1iqv, 2s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid, --alpha-methoxy-alpha-trifluoromethyl phenylacetic acid, s---mtpa, --a-methoxy-a-trifluoromethylphenylacetic acid
PubChem CID 6992788
IUPAC Name (2S)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid
SMILES CO[C@](C([O-])=O)(C1=CC=CC=C1)C(F)(F)F

Specifications

Melting Point 43°C to 45°C
Density 1.344
Boiling Point 105°C to 107°C (1 mmHg)
Flash Point >110°C (230°F)
Quantity 500 mg
Beilstein 3591561
Sensitivity Hygroscopic
Merck Index 14,6280
Solubility Information Readily soluble in hexane,ether,THF,CH2Cl2,benzene.
Optical Rotation −72° (c=2 in Methanol)
Formula Weight 234.18
Percent Purity 99%
Chemical Name or Material (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid
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Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 241-292-1
TSCA No
Recommended Storage Keep cold

RUO – Research Use Only