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Tocris Bioscience™ Ritonavir

Catalog No. 585650
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50 mg
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585650 50 mg
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Catalog No. 585650 Supplier Tocris Bioscience™ Supplier No. 5856/50
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Description

HIV-1 and HIV-2 protease inhibitor

Ritonavir is a HIV-1 and HIV-2 protease inhibitor (EC50 values are 0.022-0.13 and 0.16 μM, respectively). Blocks the metabolism of protease inhibitors by liver enzyme cytochrome P450-3A4 (CYP3A4). Orally bioavailable. When used in combination with lopinavir, improves outcome in an animal model of MERS-CoV infection.

Specifications

Chemical Name or Material 5-Thiazolylmethyl (3 S,4 S,6 S,9 S)-4-hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoate
CAS 155213-67-5
Synonym ABT-538, A-84538, Abbot 84538
Quantity 50 mg
Target HIV Protease Inhibitors
Molecular Formula C37H48N6O5S2
Formula Weight 720.94
Purity 98%