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Tocris Bioscience™ Remdesivir

Catalog No. 722650
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722650 50 mg
722610 10 mg
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Catalog No. 722650 Supplier Tocris Bioscience™ Supplier No. 7226/50

Description

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucelotide prodrug

Remdesivir is a viral RNA-dependent RNA polymerase inhibitor (RdRp) and broad spectrum antiviral nucleotide prodrug. Metabolized to active form, GS 441524 (Cat. No. 7227). Exhibits activity against a range of RNA viruses in vitro (EC50 values are 0.019, 0.07, 0.07 - 0.34, 0.086 - 0.14, and 23.15 μM against RSV, SARS-CoV, MERS-CoV, EBOV and SARS-CoV-2, respectively). Exhibits antiviral efficacy in animal models of MERS-CoV and EBOV infection.

Specifications

Chemical Name or Material 2-Ethylbutyl (2 S)-2-[[-[[(2 R,3 S,4 R,5 R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate
CAS 1809249-37-3
Quantity 50 mg
Target RNA/DNA Polymerase Inhibitors
Molecular Formula C27H35N6O8P
Purity 0.98