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Gibco™ Rat IL-13 (113 aa) Recombinant Protein, PeproTech® 
Recombinant Protein
Supplier: Gibco™ 40016L1MG
Description
Recombinant Rat IL-13 a 12.3 kDa protein consisting of 113 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.Specifications
| P42203 | |
| protein with no preservative | |
| 12.3 kDa | |
| 1 mg | |
| RUO | |
| ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600 | |
| Il13 | |
| Unconjugated | |
| TPGPVRRSTS PPVALRELIE ELSNITQDQK TSLCNSSMVW SVDLTAGGFC AALESLTNIS SCNAIHRTQR ILNGLCNQKA SDVASSPPDT KIEVAQFISK LLNYSKQLFR YGH | |
| E. coli | |
| ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| ELISA, Functional Assay, Western Blot | |
| 116553 | |
| Rat IL-13 (113 aa) | |
| E. coli | |
| <1 EU/ μg | |
| IL-13 | |
| The ED50 was determined by the dose-dependent proliferation of TF-1 cells is ≤ 5.0 ng/ml, corresponding to a specific activity of ≥ 2 x 10^5 units/mg | |
| Recombinant | |
| -20°C | |
| Lyophilized |