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Tocris Bioscience™ DSR 6434

Catalog No. 480910
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480950 50 mg
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Catalog No. 480910 Supplier Tocris Bioscience™ Supplier No. 4809/10

Description

Potent TLR7 agonist

DSR 6434 is a potent TLR7 agonist (EC50 = 7.2 nM). Activates several immune effector cells in vitro. Suppresses metastasis in vivo and enhances efficacy of radiation therapy in a model of colorectal carcinoma.

Specifications

Chemical Name or Material DSR 6434
CAS 1059070-10-8
Synonym 6-Amino-2-(butylamino)-9-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]methyl]-7,9-dihydro-8H-purin-8-one
Quantity 10 mg
Solubility Soluble to 50mM in 1eq. HCl and to 100mM in DMSO
Molecular Formula C19H28N8O2
Formula Weight 400.48
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >98%

Research Use Only. Not For Human or Veterinary Use