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  5. Tocris Bioscience™ PR 619

Tocris Bioscience™ PR 619

Catalog No. 448250
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10 mg
50 mg
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Catalog No. Quantity
448250 50 mg
448210 10 mg
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Catalog No. 448250 Supplier Tocris Bioscience™ Supplier No. 4482/50

Description

Broad spectrum DUB inhibitor

PR 619 is a broad spectrum, reversible DUB inhibitor. Exhibits limited activity against other proteases. Induces accumulation of polyubiquitinated proteins, but has no direct inhibitory effect on the proteasome. Cytotoxic in HEK293T and colorectal cancer cells. Stabilizes microtubule network in oligodendroglial cells.

Specifications

Chemical Name or Material PR 619
CAS 2645-32-1
Synonym 2,6-Diamino-3,5-dithiocyanopyridine
Quantity 50 mg
Solubility Soluble to 10mM in DMSO
Molecular Formula C7H5N5S2
Formula Weight 223.28
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >98%

Research Use Only. Not For Human or Veterinary Use