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Thermo Scientific™ PIP2:PS Lipid Kinase Substrate 
Specifically optimized for use with the Class I PI3 kinases (PIK3CA, PIK3CB, PIK3CD, and PIK3CG), this substrate consists of lipid vesicles of a 1:19 molar ratio of phosphoinositol-4,5-bisphosphate (PIP2) with phosphotidylserine (PS).
Supplier: Thermo Scientific™ PV5100
Description
Specifically optimized for use with the Class I PI3 kinases (PIK3CA, PIK3CB, PIK3CD, and PIK3CG), this substrate consists of lipid vesicles of a 1:19 molar ratio of phosphoinositol-4,5-bisphosphate (PIP2) with phosphotidylserine (PS).
For use with the Adapta™ Universal Kinase Assay (Cat. No. PV5099).
Specifications
| Biochemical ADP accumulation | |
| PIP2:PS Lipid Kinase Substrate in 50 mM HEPES pH 7.5, 3 mM MgCl2, and 1 mM EGTA. Store at -20°C. |
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| Pharma and biopharma, protein assays and analysis, target and lead identification and validation, Class I PI3 kinases (PIK3CA, PIK3CB, PIK3CD, and PIK3CG), Adapta™ Universal Kinase Assay (PV5099), drug discovery and development, kinase biology, biochemical kinase assays, Adapta™ universal kinase assays, enzyme and protein activity assays, protein assays and analysis, kinase activity | |
| Phosphoinositol-4,5-bisphosphate (PIP2) lipid vesicles with phosphotidylserine (PS) | |
| Kinase Substrate | |
| 5290, 5294 | |
| PIP2:PS Lipid Kinase Substrate | |
| –20°C | |
| PIK3CA, PIK3CG, PIK3CB, PIK3CD |
| 400nmol | |
| Fluorescence | |
| 400 nmol | |
| Lipid-Based Substrate | |
| Lipid Kinases | |
| PIP2:PS Lipid Kinase Substrate, 400nmol, consists of lipid vesicles of a 1:19 molar ratio of phosphoinositol-4,5-bisphosphate (PIP2) with phosphatidylserine (PS) | |
| Dry Ice | |
| PIK3CG, PIK3CD/PIK3R1, PIK3CA/PIK3R1 |
For Research Use Only. Not for use in diagnostic procedures.