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Thermo Scientific™ Pierce™ Traut's Reagent (2-iminothiolane)

Catalog No. pi26101
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500 mg
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Catalog No. Quantity
PI26101 500 mg
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Catalog No. PI26101 Supplier Thermo Scientific™ Supplier No. 26101
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Description

2-Iminothiolane-HCl (CAS 4781-83-3); an amine-reactive thiolation reagent to cap protein primary amines with sulfhydryl groups for immediate crosslinking.

Thermo Scientific™ Pierce Traut's Reagent is 2-iminothiolane, a small thiolation compound that reacts with primary amines (e.g., lysine side chains) to add a small spacer arm (8.1 Ås) terminated by a free sulfhydryl group.

Highlights:

  • Reacts with primary amines (lysine epsilon amino groups) at pH 7-9
  • Adds a short spacer ending in a sulfhydryl group, ready for use as a target for sulfhydryl-specific crosslinking or labeling
  • Amine-containing spacer arm preserves charge of original, modified primary amine

Specifications

Chemical Reactivity Amine
Content And Storage Storage: Upon receipt store product at 4°C with desiccant. Product shipped at ambient temperature
Label or Dye Sulfhydryl Group
Label Type Conjugating Groups
Product Line Pierce
Spacer Short (<10 Å)
Form Powder
Quantity 500 mg
Solubility DMF, DMSO
Product Type Thiophilic Adsorption Kit

For Research Use Only. Not for use in diagnostic procedures.