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Thermo Scientific™ SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))

Catalog No. PI22363
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50 mg
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Catalog No. Quantity
PI22363 50 mg
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Catalog No. PI22363 Supplier Thermo Scientific™ Supplier No. 22363
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Description

Crosslink amines to sulfhydryls with this long crosslinker composed of NHS-ester and maleimide groups at ends of an aliphatic, 12-atom (14.2A) spacer arm.

Thermo Scientific™ Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (14.2 Ås).

Highlights:

  • NHS-ester reacts with a primary amine to form a stable amide bond
  • Maleimide reacts with a sulfhydryl forming a stable thioether bond
  • More hydrophilic spacer than BMPS, GMBS, EMCS or SMPB
  • Reactive groups: NHS ester and maleimide
  • Reactive toward: amino and sulfhydryl groups

Specifications

Chemical Reactivity Amine-Sulfhydryl
Cleavable No
Description SMPH
Molecular Weight (g/mol) 379.36
PEGylated No
Spacer Arm Length 14.2 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Maleimide, NHS Ester
Spacer Medium (10 to 30 Å)
Form Solid
Quantity 50 mg
Solubility DMF, DMSO
Format Standard
Water Soluble No
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.