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Thermo Scientific™ SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))

Crosslink amines to sulfhydryls with this long crosslinker composed of NHS-ester and maleimide groups at ends of an aliphatic, 12-atom (14.2A) spacer arm.

Supplier:  Thermo Scientific™ 22363

Catalog No. PI22363


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Description

Description

Thermo Scientific™ Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (14.2 Ås).

Highlights:

  • NHS-ester reacts with a primary amine to form a stable amide bond
  • Maleimide reacts with a sulfhydryl forming a stable thioether bond
  • More hydrophilic spacer than BMPS, GMBS, EMCS or SMPB
  • Reactive groups: NHS ester and maleimide
  • Reactive toward: amino and sulfhydryl groups
Specifications

Specifications

Amine-Sulfhydryl
SMPH
No
Upon receipt store desiccated at 4°C.
Ambient
Chemical Labeling
Maleimide, NHS Ester
Solid
DMF, DMSO
No
No
379.36
14.2 Å
Yes
Pierce
Heterobifunctional
Medium (10 to 30 Å)
50 mg
Standard
Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.