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Thermo Scientific™ Pierce™ SMCC

Catalog No. PI22360
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Quantity:
50 mg
10 x 1 mg
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Catalog No. Quantity
PI22360 50 mg
PIA35394 10 x 1 mg
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Catalog No. PI22360 Supplier Thermo Scientific™ Supplier No. LSG22360
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Description

No-Weigh™ Format

Thermo Scientific™ Pierce SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane-stabilized spacer arm (8.3 Ås).

Highlights:

  • Cyclohexane bridge adds stability to the maleimide-reactive group; N-(4-carboxycyclohexylmethyl) maleimide groups are stable for 64 hours in 0.1 M sodium phosphate buffer, pH 7.0 at 4°C
  • Ideal for coupling enzymes to antibodies
  • Reactive groups: NHS-ester and maleimide
  • Reactive toward: amino and sulfhydryl groups

Specifications

Chemical Reactivity Amine-Sulfhydryl
Cleavable By Thiols
Molecular Weight (g/mol) 334.32
PEGylated No
Spacer Arm Length 8.3 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Maleimide, NHS Ester
Spacer Short (<10 Å)
Form Powder
Quantity 50 mg
Solubility DMF, DMSO
Format Standard, Single-use
Water Soluble No
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.