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Thermo Scientific™ PDPH (3-(2-pyridyldithio)propionyl hydrazide)

Catalog No. PI22301
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Quantity:
50 mg
Catalog No. Quantity
PI22301 50 mg
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Catalog No. PI22301

Supplier: Thermo Scientific™ LSG22301

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Description

Crosslink sulfhydryls to periodate-treated glycoprotein sugars via cleavable disulfide bonds using this short crosslinker containing pyridyldithiol and hydrazide groups.

Thermo Scientific™ Pierce PDPH is a short, pyridyldithiol-and-hydrazide crosslinker for reversibly conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).

Highlights:

  • Pyridyldisulfide group provides a cleavable disulfide bond
  • Oxidized carbohydrate-reactive hydrazide
  • Reactive groups: pyridyldisulfide and hydrazide
  • Reactive toward: sulfhydryl groups and carbohydrate
  • Use with EDC for reactivity toward carboxyl groups

Specifications

Chemical Reactivity Carbohydrate-Sulfhydryl
Cleavable By Thiols
Description PDPH
Molecular Weight (g/mol) 229.32
PEGylated No
Spacer Arm Length 9.2 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Hydrazide, Pyridyldisulfide
Spacer Short (<10 Å)
Form Powder
Quantity 50 mg
Solubility DMF, DMSO
Format Standard
Water Soluble No
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.