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Thermo Scientific™ PDPH (3-(2-pyridyldithio)propionyl hydrazide)

Crosslink sulfhydryls to periodate-treated glycoprotein sugars via cleavable disulfide bonds using this short crosslinker containing pyridyldithiol and hydrazide groups.

Supplier:  Thermo Scientific™ LSG22301

Catalog No. PI22301


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Description

Description

Thermo Scientific™ Pierce PDPH is a short, pyridyldithiol-and-hydrazide crosslinker for reversibly conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).

Highlights:

  • Pyridyldisulfide group provides a cleavable disulfide bond
  • Oxidized carbohydrate-reactive hydrazide
  • Reactive groups: pyridyldisulfide and hydrazide
  • Reactive toward: sulfhydryl groups and carbohydrate
  • Use with EDC for reactivity toward carboxyl groups
Specifications

Specifications

Carbohydrate-Sulfhydryl
PDPH
No
Upon receipt store desiccated at 4°C.
Ambient
Chemical Labeling
Hydrazide, Pyridyldisulfide
Powder
DMF, DMSO
No
By Thiols
229.32
9.2 Å
Yes
Pierce
Heterobifunctional
Short (<10 Å)
50 mg
Standard
Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.