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Thermo Scientific™ NHS (N-hydroxysuccinimide)

Catalog No. pi24500
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25 g
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PI24500 25 g
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Catalog No. PI24500 Supplier Thermo Scientific™ Supplier No. 24500
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Description

Prepare amine-reactive NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysuccinimide, CAS 6066-82-6.

Thermo Scientific™ Pierce NHS is pure N-hydroxysuccinimide, the essential compound needed to prepare amine-reactive NHS-ester crosslinkers or to enhance conjugation efficiencies when using the carbodiimide EDC.

Highlights:

  • Form an acyl amino ester with carboxyl groups when used the EDC
  • NHS-activated molecule reacts efficiently with primary amines, resulting in stable amide bond
  • Allows for two-step EDC reactions between carboxyl- and amine-containing molecules
  • NHS-activated molecule can be stabilized by drying, allowing manufacture of amine-reactive probes and surfaces
  • Reactive groups: NHS
  • Reactive toward: amino groups (upon activation of carboxylates)

Specifications

Chemical Reactivity Amine-Carboxyl
Cleavable No
Description NHS
Molecular Weight (g/mol) 115.09
PEGylated No
Content And Storage Upon receipt store at 4°C.
Cell Permeability Not determined
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Carbodiimide
Spacer Short (<10 Å)
Form Powder
Quantity 25 g
Solubility Water
Format Standard
Water Soluble Yes
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.