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Thermo Scientific™ NHS (N-hydroxysuccinimide)
Prepare amine-reactive NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysuccinimide, CAS 6066-82-6.
Supplier: Thermo Scientific™ 24500
Description
Thermo Scientific™ Pierce NHS is pure N-hydroxysuccinimide, the essential compound needed to prepare amine-reactive NHS-ester crosslinkers or to enhance conjugation efficiencies when using the carbodiimide EDC.
Highlights:
- Form an acyl amino ester with carboxyl groups when used the EDC
- NHS-activated molecule reacts efficiently with primary amines, resulting in stable amide bond
- Allows for two-step EDC reactions between carboxyl- and amine-containing molecules
- NHS-activated molecule can be stabilized by drying, allowing manufacture of amine-reactive probes and surfaces
- Reactive groups: NHS
- Reactive toward: amino groups (upon activation of carboxylates)
Specifications
| Amine-Carboxyl | |
| NHS | |
| No | |
| Not determined | |
| Pierce™ | |
| Heterobifunctional | |
| Short (<10 AÌ) | |
| 25 g | |
| Standard | |
| Crosslinker |
| No | |
| 115.09 | |
| Upon receipt store at 4°C. | |
| Ambient | |
| Chemical Labeling | |
| Carbodiimide | |
| Powder | |
| Water | |
| Yes |
For Research Use Only. Not for use in diagnostic procedures.