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Thermo Scientific™ Pierce™ High Capacity Endotoxin Removal Spin Columns, 0.25 mL

Catalog No. PI88273
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Catalog No. PI88273 Supplier Thermo Scientific™ Supplier No. 88273

Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

Remove endotoxins (lipopolysaccharides or LPS) from samples before mass spectrometry using spin columns of poly(e-lysine) ligand on beaded cellulose.

Reduce endotoxin levels in protein samples by greater than 99% in one hour while maximizing protein recovery with Thermo Scientific™ Pierce High Capacity Endotoxin Removal Resin.

The Pierce High Capacity Endotoxin Removal Resin combines porous cellulose beads and an FDA-approved food preservative, poly(epsilon-lysine), as an affinity ligand to selectively bind endotoxins. Endotoxin levels in protein samples are reduced by greater than 99% in as little as 1 hour using our spin cup format, and protein recovery is ≥85%. The modified polylysine affinity ligand eliminates the toxicity concerns associated with alternative technologies using polymixin B ligands and sodium deoxycholate buffers. Pierce High capacity Endotoxin Removal Resin is available as a slurry to pack a custom column that can be re-used at least 5 times with no loss in endotoxin removal efficiency. This resin is also available in a new single-use spin column format optimized for different sample volumes.

Highlights:

  • High capacity bind up to 2,000,000 EU/mL to eliminate at least 99% of endotoxins

  • Durable re-use resin up to 10 times with no loss in performance

  • Selective recover at least 85% of your protein sample

  • High performance compatible with FDA guidelines by reducing final EU concentration to less than 5 EU/mL

  • Fast our new spin cup format enables endotoxin depletion within 1 hour

  • Cleansingle-use spin columns avoid cross contamination of samples

  • Optimized spin cups are optimized for different sample volumes

  • Economical large-volume discounts available

Requires:

Endotoxin-free water

Recommended for:

Eliminate endotoxins from protein or antibody samples prior to cell transfection or animal injection

Specifications

Formulation 5mL-capacity centrifuge columns containing 0.25mL resin
Content And Storage Upon receipt store at 4°C.
Form Liquid
Product Line Pierce
Quantity 5 Columns
Target Endotoxin Removal
Type Spin Column
Stationary Phase Proprietary Ligand
Format Spin Column
Column Type Affinity, Cellulose Resin
Capacity (Metric) Up to 2,000,000 EU/mL
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For Research Use Only. Not for use in diagnostic procedures.