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Thermo Scientific™ EMCH (N-ε-maleimidocaproic acid hydrazide)

Crosslink sulfhydryls to periodate-treated glycoprotein sugars with this mid-length (11.8A) crosslinker containing maleimide and hydrazide groups.

Supplier:  Thermo Scientific™ LSG22106

Catalog No. PI22106


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Description

Description

Thermo Scientific™ Pierce EMCH is a mid-length, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).

Highlights:

  • Sulfhydryl- and oxidized carbohydrate-reactive agent
  • Covalently couple the hydrazide group of EMCH to glycoproteins and other glycoconjugates after oxidation with sodium meta-periodate
  • Reactive groups: maleimide and hydrazide
  • Reactive toward: sulfhydryl and carbonyl (oxidized carbohydrate) groups
  • Use with EDC for reactivity toward carboxyl groups
Specifications

Specifications

Carbohydrate-Sulfhydryl
EMCH
No
Upon receipt store desiccated at 4°C.
Ambient
Chemical Labeling
Amine, Hydrazide, Maleimide
Solid
Water
Yes
No
339.29
11.8 Å
Yes
Pierce™
Heterobifunctional
Medium (10 to 30 Å)
50 mg
Standard
Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.