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Thermo Scientific™ DTME (dithiobismaleimidoethane)

Catalog No. pi22335
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50 mg
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Catalog No. Quantity
PI22335 50 mg
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Catalog No. PI22335 Supplier Thermo Scientific™ Supplier No. LSG22335
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Description

Crosslink sulfhydryls to sulfhydryls (cysteine residues) with this long, cleavable crosslinker composed of maleimide groups and 11-atom (13.3A) disulfide spacer arm.

Thermo Scientific™ Pierce DTME is a mid-length, maleimide crosslinker for reversible covalent conjugation between sulfhydryl groups (e.g., protein or peptide cysteines) by reduction of the disulfide bond in the center of the spacer arm.

Highlights:

  • Cleavable by reducing agents
  • Reactive groups: maleimide (homobifunctional)
  • Reactive toward: sulfhydryl groups

Specifications

Chemical Reactivity Sulfhydryl-Sulfhydryl
Cleavable By Thiols
Description DTME
Molecular Weight (g/mol) 312.36
PEGylated No
Spacer Arm Length 13.3 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety Maleimide
Spacer Medium (10 to 30 Å)
Form Solid
Quantity 50 mg
Solubility DMF, DMSO
Format Standard
Water Soluble No
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.