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Thermo Scientific™ DMS (dimethyl suberimidate)

Crosslink amines to amines with dimethyl suberimidate (CAS 34490-86-3); composed of imidoester groups at either end of a membrane-permeable, 8-atom spacer arm.

Supplier:  Thermo Scientific™ LSG20700

Catalog No. PI20700



Description

Description

Thermo Scientific™ Pierce DMS is dimethyl suberimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of an 8-atom spacer arm.

Highlights:

  • Water-soluble
  • Rapid reaction with amines at alkaline pH values (pH 8-10)
  • Amidine bond retains net charge character of protein
  • Reversible at high pH values
  • Reactive groups: imidoester (homobifunctional)
  • Reactive toward: amino groups
Specifications

Specifications

Amine-Amine
DMS
No
Upon receipt store desiccated at 4°C.
Ambient
Chemical Labeling
Imidoester
Powder
Water
Yes
No
273.2
11.0 Å
Yes
Pierce™
Homobifunctional
Medium (10 to 30 Å)
1 g
Standard
Crosslinker
SDS
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For Research Use Only. Not for use in diagnostic procedures.