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Thermo Scientific™ DMS (dimethyl suberimidate)

Catalog No. PI20700
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PI20700 1 g
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Catalog No. PI20700 Supplier Thermo Scientific™ Supplier No. LSG20700
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Description

Crosslink amines to amines with dimethyl suberimidate (CAS 34490-86-3); composed of imidoester groups at either end of a membrane-permeable, 8-atom spacer arm.

Thermo Scientific™ Pierce DMS is dimethyl suberimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of an 8-atom spacer arm.

Highlights:

  • Water-soluble
  • Rapid reaction with amines at alkaline pH values (pH 8-10)
  • Amidine bond retains net charge character of protein
  • Reversible at high pH values
  • Reactive groups: imidoester (homobifunctional)
  • Reactive toward: amino groups

Specifications

Chemical Reactivity Amine-Amine
Cleavable No
Description DMS
Molecular Weight (g/mol) 273.2
PEGylated No
Spacer Arm Length 11.0 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety Imidoester
Spacer Medium (10 to 30 Å)
Form Powder
Quantity 1 g
Solubility Water
Format Standard
Water Soluble Yes
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.