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Tocris Bioscience™ Perifosine

Catalog No. 608750
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50 mg
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Catalog No. Quantity
608750 50 mg
608710 10 mg
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Catalog No. 608750 Supplier Tocris Bioscience™ Supplier No. 6087/50

Description

PKB/Akt inhibitor; also modulates Kv2.1 current

Perifosine is a PKB/Akt inhibitor; accumulates in and reorganizes lipid rafts disrupting Akt signaling. Also inhibits MAPK pathway and induces autophagy. Induces apoptosis in leukemia cell lines. Decreases Kv2.1 current amplitude by modulating its inactivation gating. Antitumor. Orally bioavailable.

Specifications

Chemical Name or Material Perifosine
CAS 157716-52-4
Synonym Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate
Quantity 50 mg
Solubility Soluble to 100mM in water and to 100mM in ethanol
Molecular Formula C25H52NO4P
Formula Weight 461.66
Physical Form Solid
Color White
Product Type Bioactive Small Molecule
Purity >98%
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For Research Use Only.