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  8. O-Acetylsalicylic acid, 99%

O-Acetylsalicylic acid, 99%

Catalog No. p-7020506
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Catalog No. Quantity
AAA1248822 100 g
AAA1248836 500 g
AAA124880E 2500 g
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Catalog No. AAA1248822

Supplier: Thermo Scientific Chemicals A1248822

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Description

CAS: 50-78-2 | C9H8O4 | 180.16 g/mol

O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

Solubility
Soluble in 100% ethanol (80mg/ml), DMSO (41mg/ml) or dimethyl formamide (30mg/ml); slightly soluble in Phosphate-buffered saline (PBS), pH 7.2 (2.7mg/ml).

Notes
Store at room temperature. Ensure good ventilation.

Chemical Identifiers

CAS 50-78-2
Molecular Formula C9H8O4
Molecular Weight (g/mol) 180.16
MDL Number MFCD00002430
InChI Key BSYNRYMUTXBXSQ-UHFFFAOYSA-N
Synonym aspirin, acetylsalicylic acid, 2-acetoxybenzoic acid, 2-acetyloxy benzoic acid, acetylsalicylate, o-acetylsalicylic acid, o-acetoxybenzoic acid, acylpyrin, polopiryna, easprin
PubChem CID 2244
ChEBI CHEBI:15365
IUPAC Name 2-acetyloxybenzoic acid
SMILES CC(=O)OC1=CC=CC=C1C(O)=O

Specifications

Melting Point 133°C to 140°C
Density 1.4
Flash Point 250°C (482°F)
Quantity 100 g
Beilstein 779271
Merck Index 14,851
Solubility Information Soluble in 100% ethanol (80mg/ml),DMSO (41mg/ml) or dimethyl formamide (30mg/ml); slightly soluble in Phosphate-buffered saline (PBS),pH 7.2 (2.7mg/ml).
Formula Weight 180.15
Percent Purity 99%
Chemical Name or Material O-Acetylsalicylic acid

Safety and Handling

Hazard Category H302-H500
Hazard Statement GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P264b-P270-P301+P312-P330-P501c
EINECSNumber 200-064-1
RTECSNumber VO0700000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only