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  7. N,N'-Bis(acryloyl)cystamine, Electrophoresis Reagent, 98%

N,N'-Bis(acryloyl)cystamine, Electrophoresis Reagent, 98%

Catalog No. p-7057560
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5 g
Catalog No. Quantity
AAJ6689303 1 g
AAJ6689306 5 g
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Catalog No. AAJ6689303

Supplier: Thermo Scientific Chemicals J6689303

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Description

CAS: 60984-57-8 | C10H16N2O2S2 | 260.37 g/mol

BAC is used as a reversible cross-linker for polyacrylamide gels, to simplify isolation of macromolecules separated on the gels. The disulfide linkage can be broken with a suitable reducing agent. A 1-g slice of a 4% (12:1) gel will dissolve in 5 mL of 100 mM DTT in TBE (pH 8.3) in less than 30 min. The pH of 8.3 is optimum for rapid dissolution of the gel.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
BAC is used as a reversible cross-linker for polyacrylamide gels, to simplify isolation of macromolecules separated on the gels. The disulfide linkage can be broken with a suitable reducing agent. A 1-g slice of a 4% (12:1) gel will dissolve in 5 mL of 100 mM DTT in TBE (pH 8.3) in less than 30 min. The pH of 8.3 is optimum for rapid dissolution of the gel.

Solubility
Soluble at 50 mg/ml in acetic acid

Notes
Store at -20°C. Incompatible with heat, oxidizing agents.

Chemical Identifiers

CAS 60984-57-8
Molecular Formula C10H16N2O2S2
Molecular Weight (g/mol) 260.37
MDL Number MFCD00036225
InChI Key DJVKJGIZQFBFGS-UHFFFAOYSA-N
Synonym n,n'-bis acryloyl cystamine, n,n'-bisacrylylcystamine, 2-propenamide, n,n'-dithiodi-2,1-ethanediyl bis, 2,2'-bisacrylamino diethyldisulfide, bis-acrylylcystamine: bac, n,n'-dithiodi-2,1-ethanediyl bis acrylamide, n-2-2-prop-2-enamido ethyl disulfanyl ethyl prop-2-enamide, n-2-2-prop-2-enoylamino ethyldisulfanyl ethyl prop-2-enamide, acmc-20ak9p, n,n-bis-acrylylcystamine
PubChem CID 100602
IUPAC Name N-[2-[2-(prop-2-enoylamino)ethyldisulfanyl]ethyl]prop-2-enamide
SMILES C=CC(=O)NCCSSCCNC(=O)C=C

Specifications

Melting Point 123°C to 124°C
Color White
Quantity 1 g
Solubility Information Soluble at 50mg/mL in acetic acid
Formula Weight 260.37
Percent Purity 98%
Physical Form Powder
Chemical Name or Material N,N'-Bis(acryloyl)cystamine, Electrophoresis Reagent

Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 262-546-8
TSCA No
storageNote1 −30°C to -10°C
Recommended Storage Store at -20°C; Store under Nitrogen

RUO – Research Use Only