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Tocris Bioscience™ MS 21570

Catalog No. 629810
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629810 10 mg
629850 50 mg
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Catalog No. 629810 Supplier Tocris Bioscience™ Supplier No. 6298/10
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Description

GPR171 antagonist

MS 21570 is a GPR171 antagonist (IC50 = 220 nM). Inhibits BigLEN (Cat.No. 6304) mediated increases in [35S]GTPγS binding in hypothalamic membranes and hyperpolarization of basolateral amygdala pyramidal neurons. Reduces anxiety-like behavior and fear conditioning in mice.

Specifications

Chemical Name or Material N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine
CAS 65373-29-7
Assay Percent Range >98%
Quantity 10 mg
Molecular Formula C10H11N3S2
Formula Weight Observed MW: 237.34