Thapsigargin is a naturally occurring sesquiterpene lactone isolated from the umbelliferous plant Thapsia garganica. This tumor promoter releases Ca2++ from intracellular stores by specifically inhibiting the endoplasmic reticulum Ca2++-ATPase. It does not directly affect plasma membrane Ca2++-ATPases, Ins 1,4,5-P3 production or protein kinase C activity.
Cell Analysis, Cell Structure, Cellular Imaging, Immunofluorescence (IF), Immunofluorescence Staining and Detection, Receptors
Shipping Condition: Room temperature
|Store in freezer (-5° to -30°C)|
For Research Use Only. Not for use in diagnostic procedures.