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Tocris Bioscience™ ML 120B dihydrochloride

Catalog No. 489950
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50 mg
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489950 50 mg
489910 10 mg
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Catalog No. 489950 Supplier Tocris Bioscience™ Supplier No. 4899/50
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Novel IKK2-selective inhibitor

Novel, ATP-competitive IKK2-selective inhibitor (IC50 = 60 nM at 50 μM ATP). Exhibits no inhibition at IKK1 (EC50 >100 μM), IKKε (EC50 >100 μM) or a panel of 28 other kinases (EC50 >50 μM). Exhibits antitumor activity in lymphoma-bearing SCID mice. Demonstrates synergistic cytotoxic effects with vincristine (Cat. No. 1257).

Chemical Identifiers

CAS 783348-36-7
Molecular Formula C19H15ClN4O2

Specifications

Quantity 50 mg
Formula Weight 439.72
Molecular Weight (g/mol) 366.81
Chemical Name or Material ML 120B dihydrochloride
Recommended Storage Store at +4°C