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Tocris Bioscience™ ML 120B dihydrochloride
Description
Novel, ATP-competitive IKK2-selective inhibitor (IC50 = 60 nM at 50 μM ATP). Exhibits no inhibition at IKK1 (EC50 >100 μM), IKKε (EC50 >100 μM) or a panel of 28 other kinases (EC50 >50 μM). Exhibits antitumor activity in lymphoma-bearing SCID mice. Demonstrates synergistic cytotoxic effects with vincristine (Cat. No. 1257).
Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 439.72 |
| Molecular Weight (g/mol) | 366.81 |
| Chemical Name or Material | ML 120B dihydrochloride |
Safety and Handling
| Recommended Storage | Store at +4°C |