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Tocris Bioscience™ Methoxy-X04

Catalog No. 492050
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492050 50 mg
492010 10 mg
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Description

Fluorescent amyloid β detector; brain penetrant

Methoxy-X04 is a fluorescent amyloid β (Aβ) probe for the detection and quantification of plaques, tangles and cerebrovascular amyloid. Methoxy-X04 Displays high in vitro binding affinity (Ki = 26.8 nM); binds selectively to fibrillar β-sheet deposits. Methoxy-X04 is a derivative of Congo Red (Cat. No. 5167). Methoxy-X04 can be used for in vivo Aβ plaque labeling. Methoxy-X04 co-localizes with CD68+ phagosomes in plaque-associated Iba1+ microglia; and it labels molecularly distinct plaque-associated microglia populations. Brain penetrant.

Chemical Identifiers

CAS 863918-78-9
Molecular Formula C23H20O3

Specifications

Quantity 50 mg
Formula Weight 344.4
Purity >98%
Molecular Weight (g/mol) 344.41
Chemical Name or Material Methoxy-X04

Safety and Handling

Recommended Storage Store at +4°C