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Tocris Bioscience™ MCU i4

Catalog No. 361063844
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50 mg
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Catalog No. Quantity
361063844 50 mg
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Catalog No. 361063844 Supplier Tocris Bioscience™ Supplier No. 7195/50
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Description

Negative modulator of mitochondrial Ca2+ uniporter (MCU)

MCU i4 is a negative modulator of mitochondrial calcium (Ca2+) uniporter (MCU) complex, which binds to MICU1, a regulatory protein within MCU complex. MCU i4 reduces mitochondrial Ca2+ uptake in multiple cell lines including MEFs, MDA-MB,231 and HEK293T cells, and demonstrates a negative effect on mitochondrial membrane potential. In ex vivo muscle fibres, MCU i4 reduces mitochondrial Ca2+ uptake and impairs muscle cell growth.

Specifications

Chemical Name or Material 4-[[4-(Diethylamino)phenyl]amino]-6-methyl-3-quinolinecarboxylic acid ethyl ester
CAS 371924-24-2
Quantity 50 mg
Target Mitochondrial Calcium Uniporter Inhibitors
Molecular Formula C23H27N3O2
Purity 98%