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Gibco™ Human VEGF-C Recombinant Protein, PeproTech® 
Recombinant Protein
Supplier: Gibco™ 10020CD5UG
Description
Recombinant Human VEGF-C is a disulfide-linked homodimeric protein consisting of two 13.5 kDa polypeptide chains of 116 amino acid residues. Due to glycosylation, the protein migrates as a 30.0-33.0 kDa band by SDS-PAGE analysis under non-reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.Specifications
| P49767 | |
| protein with no preservative | |
| 26.2 kDa | |
| 5 μg | |
| RUO | |
| AW228853; Flt4 ligand; FLT4 ligand DHM; Flt4-L; LMPH1D; Vascular endothelial growth factor C; vascular endothelial growth factor C isoform 129; vascular endothelial growth factor C isoform 184; vascular endothelial growth factor-related protein; VEGF3; VEGFC; VEGF-C; VRP | |
| VEGFC | |
| Unconjugated | |
| AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGVATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTSYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR | |
| HEK293 cells | |
| ≥ 95% by SDS-PAGE gel and HPLC analyses. |
| Functional Assay | |
| 7424 | |
| Human VEGF-C | |
| HEK293 cells | |
| <1 EU/ μg | |
| VEGFC | |
| Determined by its ability to stimulate the proliferation of human microvascular endothelial cells (HMVEC) in low serum conditions. | |
| Recombinant | |
| -20°C | |
| Lyophilized |