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Gibco™ Human Myostatin Propeptide Recombinant Protein, PeproTech® DFS Item

Recombinant Protein

Supplier:  Gibco™ 12012250UG

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Catalog No. 12012250UG


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Description

Description

Recombinant Human Myostatin-Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Mature myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin-Propeptide exhibits high binding affinity for myostatin, and has been shown to be a potent inhibitor of myostatin. Over-expression of myostatin-propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in myostatin knockout mice.
Specifications

Specifications

O14793
protein with no preservative
27.8 kDa
250 μg
RUO
Myostatin
MSTN
Unconjugated
MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
E. coli
≥ 98% by SDS-PAGE gel and HPLC analyses.
Functional Assay
2660
Human Myostatin Propeptide
E. coli
<1 EU/ μg
pro-Myostatin
Determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.01-0.04 ug/ml in the presence of 50 ng/ml Myostatin.
Recombinant
-20°C
Lyophilized
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