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Invitrogen™ Human Caspase-1 ELISA Kit 
ELISA
Supplier: Invitrogen™ EH70RBX5
Description
Human Caspase-1 quantitates human Caspase-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Caspase-1.
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18. Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.Specifications
| CASP1; CASP-1; CASP1 nirs variant 1; caspase 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Caspase1; caspase-1; Caspase-1 subunit p10; Caspase-1 subunit p20; ICE; IL-1 beta-converting enzyme; IL-1 B converting enzyme; IL1BC; IL-1 BC; IL1BCE; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin 1 beta converting enzyme; interleukin-1 beta convertase; interleukin-1 beta-converting enzyme; p45 | |
| 0.43 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| CASP1 | |
| <10 | |
| HRP | |
| RUO | |
| 2°C to 8°C | |
| 1 hrs 20 mins |
| 0.43 to 100 ng/mL | |
| HRP | |
| Plasma, Serum, Supernatant | |
| 834 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 5 x 96 Tests | |
| Plasma 50 μL, Serum 50 μL, Supernatant 50 μL | |
| Caspase 1 | |
| 4 hrs 45 mins |