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Tocris Bioscience™ HBX 41108

Catalog No. 428510
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10 mg
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Catalog No. Quantity
428510 10 mg
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Catalog No. 428510 Supplier Tocris Bioscience™ Supplier No. 4285/10
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Description

Selective USP7 inhibitor

Inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM). Displays uncompetitive inhibition. Also inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 μM). Stabilizes p53 and inhibits cancer cell growth; induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines.

Chemical Identifiers

CAS 924296-39-9
Molecular Formula C13H3ClN4O

Specifications

Quantity 10 mg
Formula Weight 266.64
Purity >98%
Molecular Weight (g/mol) 266.64
Chemical Name or Material HBX 41108

Safety and Handling

Recommended Storage Store at -20°C