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Tocris Bioscience™ GSK 269962
Description
Potent Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively). Displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases. Induces vasorelaxation in preconstricted rat aorta (IC50 = 35 nM); lowers blood pressure in a rat model of hypertension.
Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 570.6 |
| Purity | >99% |
| Molecular Weight (g/mol) | 570.61 |
| Chemical Name or Material | GSK 269962 |
Safety and Handling
| Recommended Storage | Store at +4°C |