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GFP-EIF2A

Catalog No. PV4809
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20 nmol
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Catalog No. Quantity
PV4809 20 nmol
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Catalog No. PV4809 Supplier Thermo Fisher Scientific Supplier No. PV4809
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Description

GFP-EIF2A

EIF2A has been expressed as a fusion with GFP (Green Fluorescent Protein) to act as a physiological substrate for the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2).

For use in combination with the LanthaScreen™ Tb-anti-eIF2alpha [pSer52] Antibody (PV4810) to evaluate inhibitors in medium to high throughput screening applications.

Specifications

Assay Entry Biochemical terbium phospho-specific activity
Content And Storage GFP-EIF2alpha protein substrate in 9 mM HEPES pH 7.5, 123 mM NaCl, 2.43 mM KCl, 10% Glycerol, 2mM DTT . Store at -80 °C.
Detection Method Fluorescence
Form Liquid
Quantity 20 nmol
Substrate EIF2A
Substrate Properties Protein-Based Substrate
Substrate Type Kinase Substrate
Target Enzyme Serine/Threonine Kinases
Gene ID (Entrez) 9833
Label or Dye GFP (EmGFP)
Molecular Weight (g/mol) 69100 Da
Shipping Condition Dry Ice
Target Entry EIF2AK1, EIF2AK2, EIF2AK3
Validated Kinases EIF2AK2, EIF2AK3
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For Research Use Only. Not for use in diagnostic procedures.