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  5. Tocris Bioscience™ GDC 0941

Tocris Bioscience™ GDC 0941

Numéro de catalogue. 890550
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890510 10 mg
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Numéro de catalogue. 890550 Fournisseur Tocris Bioscience™ Code fournisseur 8905/50
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Description

Potent pan-class I PI3 kinase inhibitor

GDC 0941 is a potent pan PI3K inhibitor of class I catalytic subunits p110α, δ, β, and γ (IC50 values are 3, 3, 33 and 75 nM, respectively). GDC 0941 inhibits the PI3K/AKT/mTOR signaling pathways and tumor cell growth in vitro and in vivo. GDC 0941 can be used in stem cell differentiation protocols to generate artery and vein endothelial cells from PSCs. GDC 0941 is orally bioavailable.

Spécifications

Chemical Name or Material 2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine
CAS 957054-30-7
Quantity 50 mg
Target PI 3-Kinase Inhibitors
Molecular Formula C23H27N7O3S2
Purity 98%