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Fluorescein-P53 (Ser15) Peptide Substrate

Catalog No. PV5132
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PV5132 1 mL
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Catalog No. PV5132 Supplier Thermo Fisher Scientific Supplier No. PV5132
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Description

Fluorescein-p53 (Ser15) Peptide Substrate

A fluorescein-labeled peptide substrate based upon p53 containing Ser15. p53 is phosphorylated at Ser15 by a wide range of kinases including PI3K/AKT pathway kinases such DNA-PK, ATM, and ATR.

For use in combination with the LanthaScreen™ Tb-anti-phospho-p53 [pSer15] antibody (PV5130) to evaluate inhibitors in medium to high throughput screening applications.

Specifications

Amino Acid Sequence Fluorescein-EPPLSQEAFADLWKK
Assay Entry Biochemical terbium phospho-specific activity
Content And Storage 1 mg/mL Fluorescein-p53 (Ser15) peptide substrates in DMSO. Store at -20° C and protect from light.
Detection Method Fluorescence
Product Line LanthaScreen
Quantity 1 mL
Substrate Fluorescein-Tb
Substrate Properties Peptide-Based Substrate
Substrate Type Kinase Substrate
Target Enzyme Serine/Threonine Kinases
Label or Dye FITC (Fluorescein)
Molecular Weight (g/mol) 2118.3 Da
Shipping Condition Dry Ice
Target Entry DNAPK
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For Research Use Only. Not for use in diagnostic procedures.